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Cross-sectional analysis of data from the U.S. clinical trials database reveals poor translational clinical trial effort for traumatic brain injury, compared with stroke.

机译：来自美国临床试验数据库的数据的横断面分析显示，与中风相比，创伤性脑损伤的翻译临床试验效果差。

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Lucia M Li; David K Menon; Tobias Janowitz;
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1. External Validation of the International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury: Prognostic Models for Traumatic Brain Injury on the Study of the Neuroprotective Activity of Progesterone in Severe Traumatic Brain Injuries Trial [J] . Sun Hong, Lingsma Hester F., Steyerberg Ewout W., Journal of neurotrauma . 2016,第16期

机译：创伤性脑损伤临床试验的预后和分析国际使命的外部验证：创伤性脑损伤试验中孕酮的神经保护活性研究对创伤性脑损伤的预后模型
2. Goldstein et al.'s Secondary Analysis of Progesterone Clinical Trial for Traumatic Brain Injury Can Only Reflect the Same Trial Design Flaws: A Response to "Very Early Administration of Progesterone Does Not Improve Neuropsychological Outcomes in Subjects with Moderate to Severe Traumatic Brain Injury'' [J] . Stein Donald G., Sayeed Lqbal, -Garcia Claudia Espinosa, Journal of neurotrauma . 2017,第13期

机译：Goldstein等人对创伤性脑损伤的孕酮临床试验的二级分析只能反映相同的试验设计缺陷：对“非常早期的黄体酮施用不会改善受试者中受试者的神经心理学结果”的反应，以中度至重度创伤性脑损伤“
3. Predicted Unfavorable Neurologic Outcome Is Overestimated by the Marshall Computed Tomography Score, Corticosteroid Randomization After Significant Head Injury (CRASH), and International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Models in Patients with Severe Traumatic Brain Injury Managed with Early Decompressive Craniectomy [J] . Charry Jose D., Tejada Jorman H., Pinzon Miguel A., World neurosurgery . 2017,第期

机译：预测不利的神经系统结果被Marshall计算机断层扫描评分，皮质类固醇随机化（崩溃）和预后的国际特派团，以及创伤性脑损伤（冲击）模型进行了严重创伤性脑损伤的临床试验早期解压缩颅骨切除术
4. A Comparative Study of 2D Image Segmentation Algorithms for Traumatic Brain Lesions Using CT Data from the ProTECTIII Multicenter Clinical Trial [C] . Shruti Jadon M.S., Owen P. Leary, Ian Pan, Conference on Imaging Informatics for Healthcare, Research, and Applications . 2020

机译：采用Protectii Multicinical临床试验的CT数据对创伤性脑病变的2D图像分割算法的对比研究
5. Sensitivity analysis - the effects of Glasgow Outcome Scale misclassification on traumatic brain injury clinical trials. [D] . Juan, Lu. 2010

机译：敏感性分析-格拉斯哥成果量表分类错误对脑外伤临床试验的影响。
6. Cross-Sectional Analysis of Data from the U.S. Clinical Trials Database Reveals Poor Translational Clinical Trial Effort for Traumatic Brain Injury Compared with Stroke [O] . Lucia M. Li, David K. Menon, Tobias Janowitz -1

机译：来自美国临床试验数据库的数据的横断面分析显示与中风相比创伤性脑损伤的转化临床试验效果较差
7. U.S. Trends of ED Visits for Pediatric Traumatic Brain Injuries: Implications for Clinical Trials [O] . Cheng Chen, Junxin Shi, Rachel Stanley, 2017

机译：小儿创伤性脑损伤的ED访问趋势：对临床试验的影响
8. Randomized Clinical Trial of Allopregnanolone for the Treatment of Severe Traumatic Brain Injury. [R] . Rogawski, M. A., Natale, J. E. 2015

机译：allopregnanolone治疗重型颅脑损伤的随机临床试验。

Cross-sectional analysis of data from the U.S. clinical trials database reveals poor translational clinical trial effort for traumatic brain injury, compared with stroke.

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